BRAFV600E mutation in papillary thyroid microcarcinoma: a meta-analysis
نویسندگان
چکیده
منابع مشابه
Thyroid hormone resistance in two patients with papillary thyroid microcarcinoma and their BRAFV600E mutation status.
Resistance to thyroid hormone (RTH) is a rare autosomal dominant hereditary disorder. Here in, we report two patients with RTH in whom differentiated thyroid cancer was diagnosed. Two patients were admitted to our clinic and their laboratory results were elevated thyroid hormone levels with unsuppressed TSH. We considered this situation thyroid hormone resistance in the light of laboratory and ...
متن کاملThe relationship between the BRAFV600E mutation in papillary thyroid microcarcinoma and clinicopathologic factors
BACKGROUND The BRAF(V600E) mutation, which accounts for about 60-80% papillary thyroid carcinoma(PTC), has been identifiedas a prognostic marker for risk stratification of PTC patients. However, the BRAF(V600E) mutation as a prognostic marker in papillary thyroid microcarcinoma (PTMC) is unclear. METHODS We performed a retrospective review of 101 patients who underwent surgery for PTMC. We st...
متن کاملThyroid papillary microcarcinoma: a descriptive and meta-analysis study.
The authors review anatomical, clinical characteristics and prevalence of thyroid microcarcinoma. Diagnostic procedures and risk factors of aggressiveness at diagnosis and during follow-up are also covered. The possible clinical, pathologic and therapeutic risk factors are analyzed by meta-analysis study. Treatment procedures by different authors and guidelines suggested by societies are reported.
متن کاملAssociation between BRAFV600E mutation and the clinicopathological features of solitary papillary thyroid microcarcinoma
The B-Raf proto-oncogene serine/threonine kinase (BRAF)V600E mutation is an important oncogene in the development of papillary thyroid carcinoma (PTC) and has been identified as a risk factor for poor prognosis in patients with PTC. However, whether the BRAFV600E mutation is a prognostic marker in patients with solitary papillary thyroid microcarcinoma (sPTMC) has not yet been established. The ...
متن کاملBRAFV600E mutation and DNA ploidy determination in fine needle aspiration biopsy of papillary thyroid microcarcinoma in a Chinese population
This study aimed to evaluate the diagnostic value of BRAFV600E mutation and DNA ploidy determination for Papillary Thyroid Micro-Carcinoma (PTMC) through fine-needle aspiration. Clinical data, including histology, patient population statistics and clinical results were gathered. Patients’ thyroid-micro-lesions were made into FNA-stained smears, DNA was extracted from the smears for different cy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrine-Related Cancer
سال: 2015
ISSN: 1351-0088,1479-6821
DOI: 10.1530/erc-14-0531